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Hirschsprung disease in children


Discussions on "Hirschsprung disease in children" in "General Health Problems" forum.


  1. #1
    ramina is offline Friends's of Penmai
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    Hirschsprung disease in children

    Hirschsprung's disease (HD) is a disorder of the abdomen that occurs when part or all of the large intestine or antecedent parts of the gastrointestinal tract have no nerves and therefore cannot function. During normal fetal development, cells from the neural crest migrate into the large intestine (colon) to form the networks of nerves called Auerbach's plexus and Meissner's plexus. In Hirschsprung's disease, the migration is not complete and part of the colon lacks these nerve bodies that regulate the activity of the colon. The affected segment of the colon cannot relax and pass stool through the colon, creating an obstruction.[1] In most affected people, the disorder affects the part of the colon that is nearest the anus. In rare cases, the lack of nerve bodies involves more of the colon. In five percent of cases, the entire colon is affected. Stomach and esophagus may be affected too. Hirschsprung's disease is also often called congenital aganglionic megacolon.

    Hirschsprung's disease occurs in about one in 5,000 children (U.S. and Japan). It is usually diagnosed in children, and affects boys more often than girls.
    Diagnosis:
    Definitive diagnosis is made by suction biopsy of the distally narrowed segment.A histologic examination of the tissue would show a lack of ganglionic nerve cells. Diagnostic techniques involve anorectal manometry,barium enema, and rectal biopsy. The suction rectal biopsy is considered the current international gold standard in the diagnosis of Hirschsprung's disease.

    Radiologic findings may also assist with diagnosis.Cineanography (fluoroscopy of contrast medium passing anorectal region) assists in determining the level of the affected intestines.

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    re: Hirschsprung disease in children

    Thank you Ramina for your efforts to educate our members regarding this disease!


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    re: Hirschsprung disease in children

    Thanks for the unknown & intresting info ramina

    Arise ! awake ! and stop not till the goal is reached

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    re: Hirschsprung disease in children

    This is my experience. Bcoz my cute son suffered this disease. First enakum therla.from birth 15daysku one time thaa motion povan.all r said this is normal.so nanum kandukala.bt after5 months drta ponen.dr scolded me a lot. Then we decided to do surgery.after surgery he is normal.enna maathi yarum firstae asaalta iruka koodathunu nan ninaiken.so itha pathi ellarum therinjikanumnu nan ninaiken....

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    re: Hirschsprung disease in children

    Thank you very much Ramina for sharing the details about this disease.

    Feel very sad that your son suffered from this disease.

    Also feel happy and satisfied that he has now recovered and is normal.

    Jayanthy





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    Re: Hirschsprung disease in children

    thanks for sharing the info. Also, happy that your son has got recovered.


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