Excessive protein in scalp linked to male baldness


Lord of Penmai
Jul 5, 2011
Excessive protein in scalp linked to male baldness

Excessive quantity of the protein Prostaglandin D2 (PGD2) in in men’s scalps may be causing hair loss, a new study says.

The finding potentially opens the way to a new line of treatment for male baldness. The protein, and its offshoot 15-dPGJ2, slows down hair growth in human and animal models.

The PGD2-related inhibition was tied to the receptor: GPR44, which could be a promising target for halting baldness in both men and women, the journal Science Translational Medicine reports.

According to a Pennsylvania statement, George Cotsarelis, professor of dermatology and study co-author from the University of Pennsylvania, said: “Although a different prostaglandin was known to increase hair growth, our findings were unexpected, as prostaglandins haven’t been thought about in relation to hair loss.”

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