Hirschsprung disease in children

Raminasivaraj

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#1
Hirschsprung's disease (HD) is a disorder of the abdomen that occurs when part or all of the large intestine or antecedent parts of the gastrointestinal tract have no nerves and therefore cannot function. During normal fetal development, cells from the neural crest migrate into the large intestine (colon) to form the networks of nerves called Auerbach's plexus and Meissner's plexus. In Hirschsprung's disease, the migration is not complete and part of the colon lacks these nerve bodies that regulate the activity of the colon. The affected segment of the colon cannot relax and pass stool through the colon, creating an obstruction.[1] In most affected people, the disorder affects the part of the colon that is nearest the anus. In rare cases, the lack of nerve bodies involves more of the colon. In five percent of cases, the entire colon is affected. Stomach and esophagus may be affected too. Hirschsprung's disease is also often called congenital aganglionic megacolon.

Hirschsprung's disease occurs in about one in 5,000 children (U.S. and Japan). It is usually diagnosed in children, and affects boys more often than girls.
Diagnosis:
Definitive diagnosis is made by suction biopsy of the distally narrowed segment.A histologic examination of the tissue would show a lack of ganglionic nerve cells. Diagnostic techniques involve anorectal manometry,barium enema, and rectal biopsy. The suction rectal biopsy is considered the current international gold standard in the diagnosis of Hirschsprung's disease.

Radiologic findings may also assist with diagnosis.Cineanography (fluoroscopy of contrast medium passing anorectal region) assists in determining the level of the affected intestines.

Moderator's Note:This Article has been published in Penmai eMagazine September 2015. You Can download & Read the magazines HERE.
 
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sumitra

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#2
Thank you Ramina for your efforts to educate our members regarding this disease!
 

Subhasreemurali

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#3
Thanks for the unknown & intresting info ramina
 

Raminasivaraj

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This is my experience. Bcoz my cute son suffered this disease. First enakum therla.from birth 15daysku one time thaa motion povan.all r said this is normal.so nanum kandukala.bt after5 months drta ponen.dr scolded me a lot. Then we decided to do surgery.after surgery he is normal.enna maathi yarum firstae asaalta iruka koodathunu nan ninaiken.so itha pathi ellarum therinjikanumnu nan ninaiken....
 

jv_66

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#5
Thank you very much Ramina for sharing the details about this disease.

Feel very sad that your son suffered from this disease.

Also feel happy and satisfied that he has now recovered and is normal.
 

Raminasivaraj

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#6
Hai friends......
i already post about hirssprug disease. ....bt athu nama ninaikira maathi ordinary illaa pa...that is a rare disease.....tamil name piravi perungudal veekam noi....pirakum pothae perunkudal (large intestine )veengi irukum.....
symptoms :1.black motion velila varathu.....2.jaundice kandipa irukum....3.stomach uppi irukum..4..poor feeding. ..
plz friends ipdi ethati one child ku neenga irukuratha kelvi patta udanae scan panitu kanji kamakodi child trust hospital ku poi paediatric surgeon ah parka solunga.....okva???
Then surgery paanuna piragum risk thaa....
adikadi diarrhea varum.....then enterocolitis nu soli athukum treatment eduthutae irukanum..

S friends....nan ellathukum treatment eduthutae irukum pothu i lost my cute chiild.....

ini ithu nadaka koodathu....en kastam entha momkum vara koodathu nu thaa i told this to u.....
then seekiram ithuku treatments and prevention find pananumnu pray panunga...
romba kasta patutom.....finally enga child ipo illa......1 week aaguthu....ennala thaanga mudila.....
so pray for that disease kaana medicine find panna.....okva?
bcoz ellarum sernnthu pray panuna kandiipa nadakum....
i miss my child (3yrs3mon).....
 

Raminasivaraj

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#7
i cant......irunthum post panrenaa disease serious purinjikonga....then god ta ini entha childkum ipdi disease kudukatheenganum pray panunga.....god ku kekatum....anttha parents ku adutha children kum chance irukunu doctors solranga.....so namalala pray panna thaa mudiyum.....
 

Raminasivaraj

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#8
Hai friends......
i already post about hirssprug disease. ....bt athu nama ninaikira maathi ordinary illaa pa...that is a rare disease.....tamil name piravi perungudal veekam noi....pirakum pothae perunkudal (large intestine )veengi irukum.....
symptoms :1.black motion velila varathu.....2.jaundice kandipa irukum....3.stomach uppi irukum..4..poor feeding. ..
plz friends ipdi ethati one child ku neenga irukuratha kelvi patta udanae scan panitu kanji kamakodi child trust hospital ku poi paediatric surgeon ah parka solunga.....okva???
Then surgery paanuna piragum risk thaa....
adikadi diarrhea varum.....then enterocolitis nu soli athukum treatment eduthutae irukanum..

S friends....nan ellathukum treatment eduthutae irukum pothu i lost my cute chiild.....

ini ithu nadaka koodathu....en kastam entha momkum vara koodathu nu thaa i told this to u.....
then seekiram ithuku treatments and prevention find pananumnu pray panunga...
romba kasta patutom.....finally enga child ipo illa......1 week aaguthu....ennala thaanga mudila.....
so pray for that disease kaana medicine find panna.....okva?
bcoz ellarum sernnthu pray panuna kandiipa nadakum....
i miss my child (3yrs3mon).....
Plz pray all...
 

Raminasivaraj

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#9
Hai friends. ....
ipo latestah stem cell therapy mullama hirschsprung disease ku soln vanthrukunu solranga. ...ipo thaa animals ku success aagirukam.....so seeekiram human being ku research success aaga plz pray all....
Ellarum sernthu pray panuna kandipa nadakumnu i believe .....
thanks friends and sis...
 

jv_66

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#10
மனசுக்கு ரொம்ப ரொம்ப கஷ்டமா இருக்கு @ramina

கடவுள் உங்களுக்கும் உங்கள் கணவருக்கும் இந்த இழப்பைத் தாங்கக்கூடிய மனசை தரட்டும் .

இந்த இழப்பை ஈடுகட்டவே முடியாது .

கூடிய சீக்கிரமே உங்களுக்கு நல்ல ஆரோக்கியமான குழந்தைகள் பிறக்க நான் ஆத்மார்த்தமாக பிரார்த்திக்கிறேன் .
 

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