IVF For PCOS

nlakshmi

Minister's of Penmai
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[h=2]PCOS and IVF Success[/h]The large majority of women with PCOS, polycystic ovarian syndrome, that have not gotten pregnant with other treatments will be able to get pregnant and have a baby with IVF (in vitro fertilization) if they are under 40 and do their IVF at a high quality clinic.
IVF clinics are not all the same - learn more about IVF pregnancy success rates.
[h=2]Controlling Multiple Pregnancy Risks with PCOS[/h]
  • Using injectable gonadotropins to treat PCOS infertility has a high risk for high-order multiple pregnancy (triplets and higher). The level of risk is unacceptable for some couples
  • Recent advances in IVF technologies have resulted in the ability to maintain high pregnancy rates while controlling multiple pregnancy risk
  • Blastocyst embryo transfer is a variant of the standard IVF treatment that is useful in controlling multiple birth rates
[h=2]Our IVF PCOS Success Rates and Statistics[/h]
  • In general, IVF success rates are excellent for cases with infertility caused by PCOS
  • In our in vitro fertilization program we see PCOS pregnancy statistics of about 60% for a live birth rate per egg retrieval (woman under age 35)
  • We have had many PCOS IVF success stories...
  • See our IVF live birth success rates
[h=2]IVF Protocols for PCOS[/h]We specialize in treating women with PCOS and have 2 IVF stimulation protocols that we commonly use with PCOS:

  1. Ganirelix with Lupron trigger protocol
  2. PCOS down-regulation protocol (below)
The down-regulation PCOS IVF protocol combines:

  • Metformin
  • Oral contraceptive pills
  • Lupron down-regulation ovarian stimulation protocol
[h=3]The calendar below shows the down-regulation protocol for PCOS[/h]
  • We use metformin, usually at a dose of 500mg 3 times daily for at least a month before starting Lupron
  • Then, oral contraceptive pills for about 21 days (last 4 days of OCP shown on calendar)
  • Lupron overlaps with the last 3 birth control pills
  • Ovarian stimulation starts after 6 or 7 "pill free" days
  • Careful control of the dose of injectable FSH hormone and cautious monitoring of the ovarian response is important with polycystic ovary cases
  • We do our very best to avoid over-responding, which can result in ovarian hyperstimulation syndrome
[TABLE="width: 100%"]
[TR="bgcolor: #BCC8E6"]
[TD="bgcolor: #FFFF00, align: center"]Sunday[/TD]
[TD="bgcolor: #FFFF00, align: center"]Monday[/TD]
[TD="bgcolor: #FFFF00, align: center"]Tuesday[/TD]
[TD="bgcolor: #FFFF00, align: center"]Wednesday[/TD]
[TD="bgcolor: #FFFF00, align: center"]Thursday[/TD]
[TD="bgcolor: #FFFF00, align: center"]Friday[/TD]
[TD="bgcolor: #FFFF00, align: center"]Saturday[/TD]
[/TR]
[TR]
[TD="bgcolor: #FF33CC, align: center"]1
OCP
[/TD]
[TD="bgcolor: #FF91E3, align: center"]2
OCP/Lupron
[/TD]
[TD="bgcolor: #FF91E3, align: center"]3
OCP/Lupron
[/TD]
[TD="bgcolor: #FF91E3, align: center"]4
OCP/Lupron
[/TD]
[TD="bgcolor: #00FFFF, align: center"]5
Lupron
[/TD]
[TD="bgcolor: #00FFFF, align: center"]6
Lupron
[/TD]
[TD="bgcolor: #00FFFF, align: center"]7
Lupron
[/TD]
[/TR]
[TR]
[TD="bgcolor: #00FFFF, align: center"]8
Lupron
[/TD]
[TD="bgcolor: #00FFFF, align: center"]9
Lupron
[/TD]
[TD="bgcolor: #00FFFF, align: center"]10
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]11
Lupron
Start ovarian stimulation
[/TD]
[TD="bgcolor: #64FFC1, align: center"]12
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]13
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]14
Lupron
[/TD]
[/TR]
[TR]
[TD="bgcolor: #64FFC1, align: center"]Day 1 of stim[/TD]
[TD="bgcolor: #64FFC1, align: center"]Day 2 of stim[/TD]
[TD="bgcolor: #64FFC1, align: center"]Day 3 of stim[/TD]
[TD="bgcolor: #64FFC1, align: center"]Day 4 of stim[/TD]
[/TR]
[TR]
[TD="bgcolor: #64FFC1, align: center"]15
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]16
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]17
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]18
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]19
Lupron
[/TD]
[TD="bgcolor: #64FFC1, align: center"]20
Lupron
HCG injection
[/TD]
[TD="bgcolor: #FFFFCC, align: center"]21[/TD]
[/TR]
[TR="bgcolor: #64FFC1"]
[TD="align: center"]Day 5 of stim[/TD]
[TD="align: center"]Day 6 of stim[/TD]
[TD="align: center"]Day 7 of stim[/TD]
[TD="align: center"]Day 8 of stim[/TD]
[TD="align: center"]Day 9 of stim[/TD]
[TD="align: center"]Day 10 of stim[/TD]
[/TR]
[TR]
[TD="bgcolor: #FFB366, align: center"]22
Egg retrieval
Day of fertilization
[/TD]
[TD="bgcolor: #FFFFCC, align: center"]23[/TD]
[TD="bgcolor: #FFFFCC, align: center"]24[/TD]
[TD="bgcolor: #A87CD3, align: center"]25
Day 3 transfer
[/TD]
[TD="bgcolor: #FFFFCC, align: center"]26[/TD]
[TD="bgcolor: #A87CD3, align: center"]27
Day 5 transfer
[/TD]
[TD="bgcolor: #FFFFCC, align: center"]28[/TD]
[/TR]
[/TABLE]
Key to table:

  • Lupron = subcutaneous injection of a medication called Lupron (GnRH agonist). This medication is taken once daily
  • HCG injection = injection of a medication called HCG, which causes the eggs to complete maturation. This is taken only once in the cycle.
  • Egg retrieval procedure = the procedure that gets eggs from the ovaries
  • Embryo transfer procedure = the procedure putting embryos back in the uterus
  • Most women need 4 to 6 visits for monitoring the stimulation (not shown on this calendar) before they get the HCG trigger shot
  • The duration of the ovarian stimulation process can be shorter or longer than shown. This example shows 10 days of stimulation before the HCG trigger
  • The average number of days of stimulation is 9-10, with a range of 7 to 14 days


Source:Advanced Fertility center of Chicago
 

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